2-bromo-5H-pyrrolo[2,3-b]pyrazine

• CAT Number: L028383
• CAS Number: 875781-43-4
• Molecular Formula: C6H4BrN3
• Molecular Weight: 198.02
• Purity: ≥95%
• IUPAC Name: 2-bromo-5H-pyrrolo[2,3-b]pyrazine
• InChI: InChI=1S/C6H4BrN3/c7-5-3-9-6-4(10-5)1-2-8-6/h1-3H,(H,8,9)
• InChIKey: KTKMLXBEBKGQGL-UHFFFAOYSA-N
• SMILES: C1=CNC2=NC=C(N=C21)Br

2-Bromo-5H-pyrrolo[2,3-b]pyrazine(CAT: L028383) is a heteroaromatic brominated compound featuring a fused pyrrole-pyrazine ring system. The bromine atom at the 2-position makes it a versatile intermediate for palladium-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Buchwald–Hartwig amination. Its rigid bicyclic structure and electron-deficient character are particularly useful in the synthesis of kinase inhibitors, antiviral agents, and other bioactive molecules. This compound is widely employed in medicinal chemistry and drug discovery as a building block for designing heterocyclic scaffolds with enhanced biological properties. Its synthetic utility makes it valuable in both pharmaceutical research and advanced materials development.