2-BROMO-5-METHOXYBENZYL BROMIDE 97

• CAT Number: M013173
• CAS Number: 19614-12-1
• Molecular Formula: C8H8Br2O
• Molecular Weight: 279.96
• Purity: ≥95%
• Synonyms: 2-Bromo-5-methoxybenzyl bromide; 1-bromo-2-(bromomethyl)-4-methoxybenzene; 2-bromo-5-methoxybenzylbromide; 4-Bromo-3-bromomethyl anisole
• Storage: -20°C
• IUPAC Name: 1-bromo-2-(bromomethyl)-4-methoxybenzene
• InChI: InChI=1S/C8H8Br2O/c1-11-7-2-3-8(10)6(4-7)5-9/h2-4H,5H2,1H3
• InChIKey: MURVUTUZSUEIGI-UHFFFAOYSA-N
• SMILES: COC1=CC(=C(C=C1)Br)CBr

2-Bromo-5-methoxybenzyl bromide (Cat No.: M013173) is an aromatic halide featuring both bromine and methoxy functional groups on a benzene ring with a bromomethyl substituent. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. The bromine atoms facilitate nucleophilic substitution and cross-coupling reactions, while the methoxy group influences reactivity and regioselectivity. Its high purity ensures reliability in research and development applications where precision and consistency in chemical behavior are critical.

Reference

1.Majumdar, K. C., S. Chakravorty, and N. De. "Palladium mediated bis-and tris-biaryl Heck coupling for the synthesis of heterocycles." Tetrahedron Letters 49.21 (2008): 3419-3422.
2.Majumdar, Krishna C., et al. "Intramolecular cyclization reaction—Palladium (0)-catalyzed cyclization is more effective than tin hydride mediated reaction." Canadian Journal of Chemistry 86.4 (2008): 325-332.
3.Majumdar, Krishna C., Buddhadeb Chattopadhyay, and Abu Taher. "New efficient synthesis of pyrido [2, 3-c] coumarin derivatives by palladium-catalyzed Heck cyclization." Synthesis 2007.23 (2007): 3647-3652.