2-Boc-6-oxo-2-azaspiro[3.3]heptane

• CAT Number: R074336
• CAS Number: 1181816-12-5
• PubChem Substance ID: 52333005
• Molecular Formula: C11H17NO3
• Molecular Weight: 211.26
• Purity: ≥95%
• IUPAC Name: tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate
• InChI: InChI=1S/C11H17NO3/c1-10(2,3)15-9(14)12-6-11(7-12)4-8(13)5-11/h4-7H2,1-3H3
• InChIKey: HQHRAGXKFOTSQE-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CC2(C1)CC(=O)C2

2-Boc-6-oxo-2-azaspiro[3.3]heptane（Cat No.:R074336）is a spirocyclic compound featuring a rigid azaspiro[3.3]heptane scaffold, a ketone at the 6-position, and a tert-butoxycarbonyl (Boc) group protecting the nitrogen atom. Its unique three-dimensional structure offers conformational constraint, making it a valuable motif in drug design to enhance metabolic stability and receptor selectivity. The Boc group allows for controlled deprotection in multistep synthesis. Frequently used in medicinal chemistry, this compound serves as a versatile intermediate for developing CNS-targeted drugs, enzyme inhibitors, and spirocyclic peptidomimetics with improved pharmacokinetic properties.