For research use only. Not for therapeutic Use.
2-Aminopurine-O-Ph-NHCO-C3-COOH hydrochloride(CAT: I040228) is a synthetic intermediate used in the preparation of the activated NHS ester derivative, 2-Aminopurine-O-Ph-NHCO-C3-NHS ester (HY-143336). Featuring a carboxylic acid functional group at the terminal end of a flexible C3 linker, this compound serves as a key precursor for amide coupling reactions. It retains the 2-aminopurine fluorophore core, enabling its use in bioconjugation and fluorescent labeling strategies after further modification. The hydrochloride salt form enhances solubility and handling. This intermediate is valuable in the synthesis of probes for nucleic acid research, site-specific labeling, and other applications requiring bioorthogonal conjugation chemistry.
| Synonyms | 5-[[4-[(2-amino-7H-purin-6-yl)oxymethyl]phenyl]methylamino]-5-oxopentanoic acid;hydrochloride |
| Molecular Formula | C18H21ClN6O4 |
| Purity | ≥95% |
| IUPAC Name | 5-[[4-[(2-amino-7H-purin-6-yl)oxymethyl]phenyl]methylamino]-5-oxopentanoic acid;hydrochloride |
| InChI | InChI=1S/C18H20N6O4.ClH/c19-18-23-16-15(21-10-22-16)17(24-18)28-9-12-6-4-11(5-7-12)8-20-13(25)2-1-3-14(26)27;/h4-7,10H,1-3,8-9H2,(H,20,25)(H,26,27)(H3,19,21,22,23,24);1H |
| InChIKey | RYGZKXIKFUHQNI-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1CNC(=O)CCCC(=O)O)COC2=NC(=NC3=C2NC=N3)N.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
