2-Amino-6-chloropurine

• CAT Number: R001144
• CAS Number: 10310-21-1
• Molecular Formula: C5H4ClN5
• Molecular Weight: 169.57
• Purity: ≥95%
• Synonyms: 6-Chloroguanine, 6-Chloro-2-aminopurine; USP Famciclovir Related Compound F
• Storage: -20°C
• IUPAC Name: 6-chloro-7H-purin-2-amine
• InChI: InChI=1S/C5H4ClN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11)
• InChIKey: RYYIULNRIVUMTQ-UHFFFAOYSA-N
• SMILES: C1=NC2=C(N1)C(=NC(=N2)N)Cl

2-Amino-6-chloropurine (Cat No.: R001144) is a purine analog with a chlorine atom at the 6-position and an amino group at the 2-position of the purine ring. It is used as an intermediate in the synthesis of nucleoside analogs and antiviral or anticancer agents. The chlorine substituent can be readily displaced in nucleophilic substitution reactions, allowing modification at the 6-position. Its structural similarity to guanine makes it valuable in studying DNA/RNA interactions and enzymatic activity involving purine metabolism or nucleotide incorporation.