2-Amino-5-bromoisonicotinic acid

• CAT Number: L043112
• CAS Number: 1000339-23-0
• Molecular Formula: C6H5BrN2O2
• Molecular Weight: 217.02
• Purity: ≥95%
• IUPAC Name: 2-amino-5-bromopyridine-4-carboxylic acid
• InChI: InChI=1S/C6H5BrN2O2/c7-4-2-9-5(8)1-3(4)6(10)11/h1-2H,(H2,8,9)(H,10,11)
• InChIKey: JJJKKHUIIDAXKW-UHFFFAOYSA-N
• SMILES: C1=C(C(=CN=C1N)Br)C(=O)O

2-Amino-5-bromoisonicotinic acid(CAT: L043112) is a halogenated pyridine derivative bearing an amino group at the 2-position, a bromine atom at the 5-position, and a carboxylic acid at the 4-position of the isonicotinic acid scaffold. This multifunctional compound is widely used as a versatile intermediate in pharmaceutical and agrochemical synthesis. The bromine allows for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald–Hartwig), while the amino and carboxylic acid groups enable further functionalization through amidation, esterification, or heterocycle formation. Its heteroaromatic core and modifiable functionalities make it ideal for designing kinase inhibitors, anti-infective agents, and other biologically active small molecules in drug discovery.