2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride

• CAT Number: M046757
• CAS Number: 1185-53-1
• Molecular Formula: C4H12ClNO3
• Molecular Weight: 157.59
• Purity: ≥95%
• Synonyms: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride
• Target: Reagents
• Solubility: Soluble to 4000 mM in sterile water
• Storage: Store at RT
• IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
• InChI: InChI=1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H
• InChIKey: QKNYBSVHEMOAJP-UHFFFAOYSA-N
• SMILES: C(C(CO)(CO)N)O.Cl

2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride (Cat No.: M046757), commonly known as Tris hydrochloride (Tris-HCl), is the hydrochloride salt of Tris, a widely used buffering agent in biological and biochemical research. It maintains stable pH in the physiological range, particularly in electrophoresis, enzyme reactions, and cell culture. The compound is highly water-soluble and provides effective buffering capacity due to its primary amine group. Tris-HCl is favored for its low UV absorbance, minimal reactivity, and compatibility with a wide range of biological systems and analytical techniques.