2-(5-Benzyl-3,6-dioxopiperazin-2-yl)acetic acid

• CAT Number: L047864
• CAS Number: 55102-13-1
• Molecular Formula: C13H14N2O4
• Molecular Weight: 262.26
• Purity: ≥95%
• IUPAC Name: 2-(5-benzyl-3,6-dioxopiperazin-2-yl)acetic acid
• InChI: InChI=1S/C13H14N2O4/c16-11(17)7-10-13(19)14-9(12(18)15-10)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7H2,(H,14,19)(H,15,18)(H,16,17)
• InChIKey: VNHJXYUDIBQDDX-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CC2C(=O)NC(C(=O)N2)CC(=O)O

2-(5-Benzyl-3,6-dioxopiperazin-2-yl)acetic acid(CAT: L047864) is a functionalized diketopiperazine derivative incorporating a benzyl-substituted piperazine-2,5-dione core linked to an acetic acid moiety. This compound is valuable in peptide chemistry and drug design due to its conformational rigidity and potential for bioactivity modulation. It serves as a key intermediate for synthesizing cyclic peptides, enzyme inhibitors, and CNS-active agents. The presence of both carboxylic acid and amide groups allows for versatile derivatization and conjugation strategies. With defined stereoelectronic properties and favorable pharmacophoric features, this molecule supports medicinal chemistry research focused on developing therapeutics with improved stability, receptor selectivity, and pharmacokinetic profiles.