2-(4-Methylphenyl)-6-methylimidazole[1,2-a]-pyridine-3-acetic Acid (Zolpidem Impurity)

• CAT Number: R006185
• CAS Number: 189005-44-5
• Molecular Formula: C17H16N2O2
• Molecular Weight: 280.33
• Purity: ≥95%
• Synonyms: 6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetic Acid; Zolpidic Acid; Zolpidem Acid
• Storage: -20°C
• IUPAC Name: 2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetic acid
• InChI: InChI=1S/C17H16N2O2/c1-11-3-6-13(7-4-11)17-14(9-16(20)21)19-10-12(2)5-8-15(19)18-17/h3-8,10H,9H2,1-2H3,(H,20,21)
• InChIKey: JHGHLTNIQXXXNV-UHFFFAOYSA-N
• SMILES: CC1=CC=C(C=C1)C2=C(N3C=C(C=CC3=N2)C)CC(=O)O

2-(4-Methylphenyl)-6-methylimidazo[1,2-a]pyridine-3-acetic acid (Cat No.: R006185) is a known impurity of zolpidem, a widely used sedative-hypnotic drug. This compound features a fused imidazo[1,2-a]pyridine core substituted with methyl and acetic acid groups, along with a para-methylphenyl ring. It arises during the synthesis or degradation of zolpidem and is monitored for quality control in pharmaceutical manufacturing. Its structural similarity to zolpidem makes it important in impurity profiling, toxicological assessment, and regulatory compliance to ensure the safety and efficacy of final drug formulations.