2-[(2,6-Dichlorophenyl)amino]benzaldehyde (Diclofenac impurity)

• CAT Number: R010289
• CAS Number: 22121-58-0
• Molecular Formula: C13H9Cl2NO
• Molecular Weight: 266.12
• Purity: ≥95%
• Synonyms: N-(2,6-Dichlorophenyl)anthranilaldehyde; 2-(2,6-Dichloroanilino)benzaldehyde; o-(2,6-Dichloroanilino)benzaldehyde; Diclofenac Aldehyde
• Storage: -20°C
• IUPAC Name: 2-(2,6-dichloroanilino)benzaldehyde
• InChI: InChI=1S/C13H9Cl2NO/c14-10-5-3-6-11(15)13(10)16-12-7-2-1-4-9(12)8-17/h1-8,16H
• InChIKey: MILOIOYXRHLAAH-UHFFFAOYSA-N
• SMILES: C1=CC=C(C(=C1)C=O)NC2=C(C=CC=C2Cl)Cl

2-[(2,6-Dichlorophenyl)amino]benzaldehyde(CAT: R010289) is a key synthetic intermediate and recognized impurity in the production of diclofenac, a widely used nonsteroidal anti-inflammatory drug (NSAID). This compound features an aldehyde group ortho to an aniline moiety substituted with a 2,6-dichlorophenyl ring, offering both electron-rich and electron-deficient sites for selective reactivity. It is primarily utilized in pharmaceutical quality control, impurity profiling, and analytical method validation to ensure product purity and regulatory compliance. The molecule’s structure makes it useful in studies of degradation pathways and synthetic optimization of diclofenac.