2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl Methanesulfonate

• CAT Number: R031016
• CAS Number: 160969-03-9
• Molecular Formula: C11H13F3O5S
• Molecular Weight: 314.28
• Purity: ≥95%
• Synonyms: 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]-ethanol Methanesulfonate; 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]-ethanol 1-Methanesulfonate
• Storage: -20°C
• IUPAC Name: 2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl methanesulfonate
• InChI: InChI=1S/C11H13F3O5S/c1-20(15,16)19-7-6-17-9-4-2-3-5-10(9)18-8-11(12,13)14/h2-5H,6-8H2,1H3
• InChIKey: HOJMCBMXHWZNKX-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)OCCOC1=CC=CC=C1OCC(F)(F)F

2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate (Cat No.: R031016) is an organic compound featuring a trifluoroethoxy-substituted phenyl ether linked to an ethyl methanesulfonate moiety. This molecule serves as a reactive intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty materials. The methanesulfonate (mesylate) group is a good leaving group, enabling efficient nucleophilic substitution reactions. The trifluoroethoxy group enhances lipophilicity and metabolic stability, making the compound valuable in drug design for modifying pharmacokinetic properties or incorporating fluorinated motifs into biologically active molecules.