2′,3′-Di-O-acetylguanosine

• CAT Number: I044462
• CAS Number: 42167-65-7
• Molecular Formula: C14H17N5O7
• Molecular Weight: 367.31
• Purity: ≥95%
• Synonyms: [(2R,3R,4R,5R)-4-acetyloxy-5-(2-amino-6-oxo-1H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] acetate
• InChI: InChI=1S/C14H17N5O7/c1-5(21)24-9-7(3-20)26-13(10(9)25-6(2)22)19-4-16-8-11(19)17-14(15)18-12(8)23/h4,7,9-10,13,20H,3H2,1-2H3,(H3,15,17,18,23)/t7-,9-,10-,13-/m1/s1
• InChIKey: MESNVKGXLMWATF-QYVSTXNMSA-N
• SMILES: CC(=O)O[C@@H]1[C@H](O[C@H]([C@@H]1OC(=O)C)N2C=NC3=C2N=C(NC3=O)N)CO

2′,3′-Di-O-acetylguanosine（Cat No.:I044462）is a chemically modified nucleoside in which the hydroxyl groups at the 2′ and 3′ positions of the ribose moiety are acetylated. This structural modification enhances the compound’s lipophilicity, stability, and cellular permeability, making it useful in nucleoside-based drug design and prodrug development. As a derivative of guanosine, it can serve as a precursor in the synthesis of antiviral and anticancer agents or as a probe in biochemical studies involving RNA metabolism and nucleoside transport. It supports research in medicinal chemistry and nucleic acid-related therapeutic development.