(1S,4R) Sertraline Hydrochloride

• CAT Number: R008497
• CAS Number: 79896-31-4
• Molecular Formula: C17H18Cl3N
• Molecular Weight: 342.688
• Purity: ≥95%
• Synonyms: (1S,4R)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine Hydrochloride; (1S-trans)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-?-naphthalenamine Hydrochloride
• Storage: Desiccate at RT
• IUPAC Name: (1S,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride
• InChI: InChI=1S/C17H17Cl2N.ClH/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11;/h2-6,8,10,12,17,20H,7,9H2,1H3;1H/t12-,17+;/m1./s1
• InChIKey: BLFQGGGGFNSJKA-KELGLJHESA-N
• SMILES: CNC1CCC(C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl

(1S,4R) Sertraline Hydrochloride (CAS 79896-31-4) is an anti-depressant and an enantiomer 1S,4R of Sertraline.

Reference

1.Wozniak, Timothy J., Ronald J. Bopp, and Eric C. Jensen. "Chiral drugs: an industrial analytical perspective." Journal of pharmaceutical and biomedical analysis 9.5 (1991): 363-382.
2.Kudo, K., et al. "Determination of enantiomeric purity of hyoscyamine from scopolia extract using HPLC-CD system without chiral separation." Enantiomer 5.3-4 (2000): 369-375.
3.Adams, A. I. H., and A. M. Bergold. "Assay of sertraline in tablets and drug substance by liquid chromatography." Journal of pharmaceutical and biomedical analysis 26.3 (2001): 505-508.