(1S)-(+)-10-Camphorsulfonic Acid

• CAT Number: R011602
• CAS Number: 3144-16-9
• Molecular Formula: C₁₀H₁₆O₄S
• Molecular Weight: 232.32
• Purity: ≥95%
• Synonyms: (1S,4R)-7,7-Dimethyl-2-oxo-bicyclo[2.2.1]heptane-1-methanesulfonic Acid; (+)-Camphor-10-sulfonic Acid; (+)-β-Camphorsulfonic Acid; Reychler’s Acid; d-10-Camphorsulfonic Acid
• Storage: -20°C
• IUPAC Name: [(1S,4R)-7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl]methanesulfonic acid
• InChI: InChI=1S/C10H16O4S/c1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h7H,3-6H2,1-2H3,(H,12,13,14)/t7-,10-/m1/s1
• InChIKey: MIOPJNTWMNEORI-GMSGAONNSA-N
• SMILES: CC1([C@@H]2CC[C@]1(C(=O)C2)CS(=O)(=O)O)C

(1S)-(+)-10-Camphorsulfonic Acid (CAT: R011602) is a chiral sulfonic acid derived from camphor, widely used as a resolving agent and organocatalyst in asymmetric synthesis. With a rigid bicyclic structure and strong Brønsted acidity, CSA facilitates enantioselective transformations, including esterifications, acetal formations, and asymmetric reductions. It is especially valuable in the resolution of racemic amines and alcohols, forming crystalline diastereomeric salts. Its high thermal and chemical stability, combined with its enantiopure form, make it a preferred choice in both academic and industrial synthesis. CSA is an essential reagent for stereocontrolled synthesis, pharmaceutical development, and chiral compound analysis.