(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride

• CAT Number: R029483
• CAS Number: 1156491-10-9
• Molecular Formula: C9H10ClF2N
• Molecular Weight: 205.63
• Purity: ≥95%
• Storage: Desiccate at +4C
• IUPAC Name: (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine;hydrochloride
• InChI: InChI=1S/C9H9F2N.ClH/c10-7-2-1-5(3-8(7)11)6-4-9(6)12;/h1-3,6,9H,4,12H2;1H/t6-,9+;/m0./s1
• InChIKey: IMYLOCHFFLYHPS-RDNZEXAOSA-N
• SMILES: C1C(C1N)C2=CC(=C(C=C2)F)F.Cl

(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride(CAT: R029483) is a chiral cyclopropylamine derivative featuring a 3,4-difluorophenyl substituent and existing as the (1R,2S) stereoisomer. The compound is typically provided as its hydrochloride salt, enhancing its stability and solubility in aqueous and polar solvents. Its unique structure—combining ring strain, chirality, and electron-withdrawing fluorine atoms—makes it a valuable intermediate in pharmaceutical research, particularly in the design of central nervous system (CNS) agents, monoamine transporter inhibitors, or other bioactive small molecules. It is often explored for its conformational rigidity and metabolic resilience.