1,8-Diaminotriethyleneglycol

• CAT Number: R006298
• CAS Number: 929-59-9
• Molecular Formula: C6H16N2O2
• Molecular Weight: 148.21
• Purity: ≥95%
• Synonyms: 2,2’-[1,2-Ethanediylbis(oxy)]bis-ethanamine; 1,2-Bis(2-aminoethoxy)ethane; 1,8-Diamino-3,6-dioxaoctane; 2,2’-(Ethylenedioxy)bis(ethylamine); 2,2’-(Ethylenedioxy)diethylamine; NSC 28972
• Target: PROTAC Linkers
• Storage: Desiccate at +4C
• IUPAC Name: 2-[2-(2-aminoethoxy)ethoxy]ethanamine
• InChI: InChI=1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2
• InChIKey: IWBOPFCKHIJFMS-UHFFFAOYSA-N
• SMILES: C(COCCOCCN)N

1,8-Diaminotriethyleneglycol(CAT: R006298) is a bifunctional polyethylene glycol (PEG) derivative containing terminal primary amine groups and a flexible triethylene glycol backbone. This compound is widely used as a hydrophilic linker or spacer in bioconjugation, polymer modification, and surface functionalization. Its amine functionalities enable efficient coupling with carboxylic acids, activated esters, or isocyanates, making it ideal for synthesizing PEGylated biomolecules, dendrimers, and crosslinked polymers. The triethylene glycol segment provides water solubility and biocompatibility, enhancing molecular mobility and reducing non-specific binding. Commonly employed in drug delivery systems, nanomaterials, and biomedical research, it supports precise molecular architecture and tunable physicochemical properties.