For research use only. Not for therapeutic Use.
18β-Glycyrrhetinic acid(CAT: R048750) is a naturally derived triterpenoid obtained from the hydrolysis of glycyrrhizin, the major active component of licorice root (Glycyrrhiza glabra). It exhibits a broad range of biological activities, including anti-inflammatory, antiviral, antioxidant, and anticancer effects. Widely used in pharmaceutical, nutraceutical, and cosmetic formulations, it acts by inhibiting enzymes like 11β-hydroxysteroid dehydrogenase, thereby enhancing endogenous corticosteroid activity. Its structure, based on the oleanane skeleton, enables it to modulate cell signaling and immune responses.
| CAS Number | 471-53-4 |
| Synonyms | (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid |
| Molecular Formula | C30H46O4 |
| Purity | ≥95% |
| IUPAC Name | (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid |
| InChI | InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,22-,23+,26+,27-,28-,29+,30+/m0/s1 |
| InChIKey | MPDGHEJMBKOTSU-YKLVYJNSSA-N |
| SMILES | CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
