17a-Hydroxyprogesterone Valerate (Cat No.:C001117) is a synthetic progestin, derived from 17a-hydroxyprogesterone, a naturally occurring hormone. It is a progestational agent used in hormone replacement therapy and as a contraceptive. The valerate ester modification enhances its stability and bioavailability when administered orally or via injection. This compound mimics the actions of progesterone in the body, regulating the menstrual cycle and supporting pregnancy.
| Catalog Number | C001117 |
| CAS Number | 6677-15-2 |
| Synonyms | 17-Hydroxypregn-4-ene-3,20-dione Valerate |
| Molecular Formula | C₂₆H₃₈O₄ |
| Purity | 95% |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Storage | -20°C, Inert atmosphere |
| IUPAC Name | [(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] pentanoate |
| InChI | InChI=1S/C26H38O4/c1-5-6-7-23(29)30-26(17(2)27)15-12-22-20-9-8-18-16-19(28)10-13-24(18,3)21(20)11-14-25(22,26)4/h16,20-22H,5-15H2,1-4H3/t20-,21+,22+,24+,25+,26+/m1/s1 |
| InChIKey | BQUKFPPRDXJLJV-WYKXONHLSA-N |
| SMILES | CCCCC(=O)OC1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)C(=O)C |
| Reference | Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003), |
