For research use only. Not for therapeutic Use.
17-Phenyl trinor Prostaglandin F2α methyl amide(Cat No.:R017492)is a synthetic analog of the naturally occurring prostaglandin F2α, structurally modified with a phenyl group at the 17-position, a methyl amide at the terminal carboxyl, and a trinor backbone lacking three terminal carbon atoms. These modifications enhance its metabolic stability, receptor selectivity, and lipophilicity, making it suitable for therapeutic applications such as glaucoma treatment by lowering intraocular pressure. It mimics the biological activity of prostaglandins by interacting with FP receptors, influencing smooth muscle contraction and aqueous humor outflow in ocular tissues.
CAS Number | 155206-01-2 |
Molecular Formula | C24H35NO4 |
Purity | ≥95% |
Storage | -20°C |
IUPAC Name | (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-methylhept-5-enamide |
InChI | InChI=1S/C24H35NO4/c1-25-24(29)12-8-3-2-7-11-20-21(23(28)17-22(20)27)16-15-19(26)14-13-18-9-5-4-6-10-18/h2,4-7,9-10,15-16,19-23,26-28H,3,8,11-14,17H2,1H3,(H,25,29)/b7-2-,16-15+/t19-,20+,21+,22-,23+/m0/s1 |
InChIKey | UWIWNJFBNIMMGY-FDBOBMRISA-N |
SMILES | CNC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/[C@H](CCC2=CC=CC=C2)O)O)O |
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