15-LOX-1 inhibitor 1

• CAT Number: I044459
• CAS Number: 2349374-37-2
• Molecular Formula: C22H21ClN2O4
• Molecular Weight: 412.87
• Purity: ≥95%
• Synonyms: ethyl 6-chloro-3-[(E)-3-[(2-methoxyphenyl)methylamino]-3-oxoprop-1-enyl]-1H-indole-2-carboxylate
• InChI: InChI=1S/C22H21ClN2O4/c1-3-29-22(27)21-17(16-9-8-15(23)12-18(16)25-21)10-11-20(26)24-13-14-6-4-5-7-19(14)28-2/h4-12,25H,3,13H2,1-2H3,(H,24,26)/b11-10+
• InChIKey: BRMZRDPEXXAZRV-ZHACJKMWSA-N
• SMILES: CCOC(=O)C1=C(C2=C(N1)C=C(C=C2)Cl)/C=C/C(=O)NCC3=CC=CC=C3OC

15-LOX-1 inhibitor 1（Cat No.:I044459）is a selective small-molecule inhibitor targeting 15-lipoxygenase-1 (15-LOX-1), an enzyme involved in the oxidative metabolism of polyunsaturated fatty acids such as linoleic and arachidonic acid. By blocking 15-LOX-1 activity, this compound reduces the production of pro-inflammatory lipid mediators, including 13-HODE and 15-HETE, which are implicated in inflammation, cancer, and metabolic disorders. 15-LOX-1 inhibitor 1 is a valuable research tool for exploring the role of lipid signaling in disease progression and supports therapeutic development in inflammation-driven conditions, including asthma, atherosclerosis, and colorectal cancer.