15-Keto Travoprost

• CAT Number: R053380
• CAS Number: 404830-45-1
• Molecular Formula: C26H33F3O6
• Molecular Weight: 498.50
• Purity: ≥95%
• Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; 15-keto Fluprostenol Isopropyl Ester
• Target: Drug Metabolite
• Storage: -20°C
• IUPAC Name: propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate
• InChI: InChI=1S/C26H33F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,21-24,31-32H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12+/t21-,22-,23+,24-/m1/s1
• InChIKey: KSDDYCRRTVADFZ-OHDKTVHDSA-N
• SMILES: CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/C(=O)COC2=CC=CC(=C2)C(F)(F)F)O)O

15-Keto Travoprost（Cat No.:R053380）is a metabolic derivative of travoprost, a prostaglandin F2α analog used primarily to reduce intraocular pressure in glaucoma and ocular hypertension. This compound features a ketone group at the 15-position, resulting from enzymatic oxidation during metabolism. While it retains structural similarity to the parent drug, 15-keto travoprost has significantly reduced or no pharmacological activity at prostaglandin receptors. It is primarily studied in pharmacokinetic and metabolic profiling to understand drug clearance and activity duration. Its analysis aids in evaluating the safety and effectiveness of prostaglandin-based ocular therapies.