1,4,8-Tri-Boc-1,4,8,11-tetraazacyclotetradecane

• CAT Number: M037580
• CAS Number: 170161-27-0
• Molecular Formula: C25H48N4O6
• Molecular Weight: 500.68
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: tritert-butyl 1,4,8,11-tetrazacyclotetradecane-1,4,8-tricarboxylate
• InChI: InChI=1S/C25H48N4O6/c1-23(2,3)33-20(30)27-15-11-16-29(22(32)35-25(7,8)9)19-18-28(14-10-12-26-13-17-27)21(31)34-24(4,5)6/h26H,10-19H2,1-9H3
• InChIKey: FIPOUUYFPSMVMX-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCCNCCN(CCCN(CC1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

1,4,8-Tri-Boc-1,4,8,11-tetraazacyclotetradecane (Cat No.: M037580) is a macrocyclic tetraamine derivative where three of the four nitrogen atoms are protected with tert-butoxycarbonyl (Boc) groups. This structure is based on cyclam (1,4,8,11-tetraazacyclotetradecane) and is widely used in coordination chemistry, chelator design, and supramolecular chemistry. The Boc protection enables selective functionalization of the macrocycle and facilitates controlled metal complexation, particularly for transition metals. It is valuable in applications such as radiopharmaceuticals, metal ion sensors, and drug delivery systems targeting specific biological environments.