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14-Norlanosterol

14-Norlanosterol

  • CAT Number: R021701
  • CAS Number: 7448-02-4
  • Molecular Formula: C29H48O
  • Molecular Weight: 412.702
  • Purity: ≥95%
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<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">14-Norlanosterol(CAS&nbsp;7448-02-4)&nbsp;acts as an intermediate in cholesterol biosynthesis.&nbsp;It is used to stimulate oocytes for meiosis.14-</span></span></span><span style="color: rgb(0, 0, 0); font-family: arial, helvetica, sans-serif;">Norlanosterol</span><span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">&nbsp;modulates cumulus expansion.&nbsp;</span></span></span>

Catalog Number R021701
CAS Number 7448-02-4
Molecular Formula

C29H48O

Purity 95%
Storage -20°C
IUPAC Name (3S,5R,10S,13R,14R,17R)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol
InChI InChI=1S/C29H48O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,20,22-23,25-26,30H,8,10-18H2,1-7H3/t20-,22-,23+,25+,26+,28-,29-/m1/s1
InChIKey CHGIKSSZNBCNDW-QGBOJXOESA-N
SMILES CC(CCC=C(C)C)C1CCC2C1(CCC3=C2CCC4C3(CCC(C4(C)C)O)C)C
Reference

<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">1.Dyke, Stanley Frederick.&nbsp;<i style="font-family: Arial, sans-serif; font-size: 13px;">The chemistry of the vitamins</i>. No. QP801. V5 D95. 1965.<br />
2.Strauss III, Jerome F., and Robert L. Barbieri.&nbsp;<i style="font-family: Arial, sans-serif; font-size: 13px;">Yen &amp; Jaffe&#39;s Reproductive Endocrinology: Physiology, Pathophysiology, and Clinical Management (Expert Consult-Online and Print)</i>. Elsevier Health Sciences, 2013.<br />
3.Sukhanova, Anna, et al. &quot;Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.&quot;&nbsp;<i style="font-family: Arial, sans-serif; font-size: 13px;">Cancer discovery</i>&nbsp;3.1 (2013): 96-111.</span></span></span>

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