[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene] Dichloro(o-isopropoxyphenylmethylene)rutheniu

• CAT Number: R025943
• CAS Number: 301224-40-8
• Molecular Formula: C31H38Cl2N2ORu
• Molecular Weight: 626.63
• Purity: ≥95%
• Synonyms: (SP-5-41)-[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro[[2-(1-methylethoxy-κO)phenyl]methylene-κC]ruthenium; (1,3-Dimesityl-2-imidazolidinylidene)(o-isopropoxyphenylmethylene)ruthenium Dichloride; Grubbs-Hoveyda 2nd Generation Cataly
• Storage: Store at -20C
• IUPAC Name: [1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene]-dichloro-[(2-propan-2-yloxyphenyl)methylidene]ruthenium
• InChI: InChI=1S/C21H26N2.C10H12O.2ClH.Ru/c1-14-9-16(3)20(17(4)10-14)22-7-8-23(13-22)21-18(5)11-15(2)12-19(21)6;1-8(2)11-10-7-5-4-6-9(10)3;;;/h9-12H,7-8H2,1-6H3;3-8H,1-2H3;2*1H;/q;;;;+2/p-2
• InChIKey: ZRPFJAPZDXQHSM-UHFFFAOYSA-L
• SMILES: CC1=CC(=C(C(=C1)C)N2CCN(C2=[Ru](=CC3=CC=CC=C3OC(C)C)(Cl)Cl)C4=C(C=C(C=C4C)C)C)C

[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene] dichloro(o-isopropoxyphenylmethylene)ruthenium(CAT: R025943), commonly known as a second-generation Grubbs-Hoveyda catalyst, is a highly efficient transition metal complex used in olefin metathesis reactions. Featuring an N-heterocyclic carbene (NHC) ligand and a chelating benzylidene moiety with an ortho-isopropoxy group, this catalyst offers excellent thermal stability, high activity, and functional group tolerance. It is widely employed in ring-closing metathesis (RCM), cross-metathesis (CM), and ring-opening metathesis polymerization (ROMP) for the synthesis of pharmaceuticals, polymers, and complex organic molecules. Its well-defined structure supports reproducible catalytic performance, making it a reliable tool in both academic and industrial synthetic chemistry.