1,3-Bis(2-chloroethyl)urea

• CAT Number: R022821
• CAS Number: 2214-72-4
• Molecular Formula: C5H10Cl2N2O
• Molecular Weight: 185.05
• Purity: ≥95%
• Synonyms: 1,3-Bis(2-chloroethyl)urea; 1,3-Bis(2-chloroethyl)urea; NSC 36198; Carmustine Related Compound A
• Storage: Store at RT
• IUPAC Name: 1,3-bis(2-chloroethyl)urea
• InChI: InChI=1S/C5H10Cl2N2O/c6-1-3-8-5(10)9-4-2-7/h1-4H2,(H2,8,9,10)
• InChIKey: VBWBRZHAGLZNST-UHFFFAOYSA-N
• SMILES: C(CCl)NC(=O)NCCCl

1,3-Bis(2-chloroethyl)urea（Cat No.:R022821）is a bifunctional alkylating agent featuring two 2-chloroethyl groups attached to a central urea moiety. This compound is structurally related to nitrogen mustards and exhibits potent cytotoxic properties by forming DNA cross-links, thereby inhibiting replication and transcription. It has been studied for its antineoplastic activity and potential use in chemotherapy. Its ability to disrupt nucleic acid structure makes it a valuable tool in cancer research and drug development. Additionally, it serves as a chemical intermediate in synthesizing more complex therapeutic agents with targeted alkylating functionalities.