1,2-<wbr></wbr>Dioleyloxy-<wbr></wbr>3-<wbr></wbr>dimethylamino-<wbr></wbr>propane is a cationic lipid containing the unsaturated long-<wbr></wbr>chain (18:1) oleic acid inserted at both the <em>sn</em>-<wbr></wbr>1 and <em>sn</em>-<wbr></wbr>2 positions. It has been used in the composition of lipospomes formulated as stable nucleic acid lipid particles that can encapsulate siRNA or other small molecules to be used for drug delivery.
| Catalog Number | R064976 |
| CAS Number | 104162-47-2 |
| Synonyms | DODMA;MBN 305A |
| Molecular Formula | C41H81NO2 |
| Purity | 95% |
| Storage | -20°C |
| IUPAC Name | N,N-dimethyl-2,3-bis(octadec-9-enoxy)propan-1-amine |
| InChI | InChI=1S/C41H81NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-43-40-41(39-42(3)4)44-38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h19-22,41H,5-18,23-40H2,1-4H3 |
| InChIKey | GLGLUQVVDHRLQK-UHFFFAOYSA-N |
| SMILES | CCCCCCCCC=CCCCCCCCCOCC(CN(C)C)OCCCCCCCCC=CCCCCCCCC |
| Reference | 1.Fenske, D.B.,Chonn, A., and Cullis, P.R. Liposomal nanomedicines: An emerging field. Toxicologic Pathology 36(1), 21-29 (2008). |
