1,2-Dimethoxyethane (Cat No.:R018813), also known as ethylene glycol dimethyl ether, is a clear, colorless, and highly polar aprotic solvent with the molecular formula C<sub>4</sub>H<sub>10</sub>O<sub>2</sub>. It features two methoxy groups attached to a two-carbon ethylene backbone. DME is miscible with water and most organic solvents, making it highly versatile in chemical synthesis. It is widely used as a coordinating solvent in organometallic reactions, lithium battery electrolytes, and polymer chemistry. Its ability to solvate cations enhances reaction rates, particularly in Grignard and nucleophilic substitution reactions, making it a valuable tool in both laboratory and industrial settings.