For research use only. Not for therapeutic Use.
12-Deoxywithastramonolide（Cat No.:I044919）is a naturally occurring withanolide, a class of steroidal lactones primarily found in Withania somnifera (Ashwagandha), a key herb in Ayurvedic medicine. Lacking a hydroxyl group at the 12-position, this compound retains the characteristic ergostane backbone and exhibits notable bioactivities, including anti-inflammatory, antioxidant, and anticancer effects. It interacts with cellular signaling pathways such as NF-κB and MAPK, contributing to its immunomodulatory and cytoprotective roles. 12-Deoxywithastramonolide is being explored for its therapeutic potential in managing stress-related disorders, neurodegeneration, and tumor progression, making it valuable in herbal and pharmaceutical research.
| CAS Number | 60124-17-6 |
| Synonyms | (1S,2S,4S,5R,10R,11S,14R,15R,18S)-5-hydroxy-15-[(1S)-1-[(2R)-5-(hydroxymethyl)-4-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-10,14-dimethyl-3-oxapentacyclo[9.7.0.02,4.05,10.014,18]octadec-7-en-9-one |
| Molecular Formula | C28H38O6 |
| Purity | ≥95% |
| IUPAC Name | (1S,2S,4S,5R,10R,11S,14R,15R,18S)-5-hydroxy-15-[(1S)-1-[(2R)-5-(hydroxymethyl)-4-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-10,14-dimethyl-3-oxapentacyclo[9.7.0.02,4.05,10.014,18]octadec-7-en-9-one |
| InChI | InChI=1S/C28H38O6/c1-14-12-20(33-25(31)16(14)13-29)15(2)17-7-8-18-22-19(9-11-26(17,18)3)27(4)21(30)6-5-10-28(27,32)24-23(22)34-24/h5-6,15,17-20,22-24,29,32H,7-13H2,1-4H3/t15-,17+,18-,19-,20+,22-,23-,24-,26+,27-,28-/m0/s1 |
| InChIKey | AWVMHXZWAKRDGG-MEBIVHGNSA-N |
| SMILES | CC1=C(C(=O)O[C@H](C1)[C@@H](C)[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3[C@H]5[C@H](O5)[C@@]6([C@@]4(C(=O)C=CC6)C)O)C)CO |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
