11R-VIVIT TFA

For research use only. Not for therapeutic Use.

  • CAT Number: I045794
  • Molecular Formula: C147H259N67O36S
  • Molecular Weight: 3573.15
  • Purity: ≥95%
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11R-VIVIT TFA(Cat No.:I045794)is a synthetic peptide inhibitor that selectively blocks the interaction between NFAT (nuclear factor of activated T-cells) and calcineurin, thereby preventing NFAT dephosphorylation and nuclear translocation. The VIVIT sequence confers high specificity for calcineurin binding, while the 11-arginine (11R) sequence enhances cell penetration. Supplied as a trifluoroacetate (TFA) salt, it offers improved solubility and stability. 11R-VIVIT TFA is widely used in immunology and cell signaling research to dissect calcineurin–NFAT pathways, T-cell activation, and therapeutic strategies for autoimmune diseases, inflammation, and transplant rejection.

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