1,1,3-Tribromoacetone

• CAT Number: I045309
• CAS Number: 3475-39-6
• Molecular Formula: C3H3Br3O
• Molecular Weight: 294.77
• Purity: ≥95%
• Synonyms: 1,1,3-tribromopropan-2-one
• InChI: InChI=1S/C3H3Br3O/c4-1-2(7)3(5)6/h3H,1H2
• InChIKey: FNYCCOFOQIUTIM-UHFFFAOYSA-N
• SMILES: C(C(=O)C(Br)Br)Br

1,1,3-Tribromoacetone (Cat No.: I045309) is a halogenated organic compound with the molecular formula C₃H₃Br₃O. It is a yellowish liquid known for its strong, pungent odor and lachrymatory (tear-inducing) effects. Structurally, it contains three bromine atoms—two on the first carbon and one on the third—attached to a central ketone group. This compound is primarily used in chemical synthesis and research, especially in the development of halogenated intermediates. Due to its irritant properties, it must be handled with proper safety precautions in controlled environments.

Reference

[1]. Balwant Singh, et al. Process for the preparation of high purity methotrexate and derivatives thereof. Patent US4374987A 87A

[2]. [2].Swierkot J, et al. Methotrexate in rheumatoid arthritis. Pharmacol Rep. 2006 Jul-Aug;58(4):473-92
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[3]. Banji D, et al. Evaluation of the concomitant use of methotrexate and curcumin on Freund’s complete adjuvant-induced arthritis and hematological indices in rats. Indian J Pharmacol. 2011;43(5):546-550.
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