1,1,1-Trifluoroethyl-PEG4-Tos

• CAT Number: I016005
• CAS Number: 1872433-61-8
• Molecular Formula: C17H25F3O7S
• Molecular Weight: 430.44
• Purity: ≥95%
• Synonyms: 2-[2-[2-[2-(2,2,2-trifluoroethoxy)ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
• InChI: InChI=1S/C17H25F3O7S/c1-15-2-4-16(5-3-15)28(21,22)27-13-12-25-9-8-23-6-7-24-10-11-26-14-17(18,19)20/h2-5H,6-14H2,1H3
• InChIKey: UYAXEKCLHRTXQU-UHFFFAOYSA-N
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCOCC(F)(F)F

1,1,1-Trifluoroethyl-PEG4-Tos（Cat No.:I016005）is a heterobifunctional polyethylene glycol derivative featuring a trifluoroethyl group on one end and a tosyl (Tos) leaving group on the other, linked through a four-unit PEG chain. The trifluoroethyl moiety imparts increased lipophilicity and chemical stability, while the tosyl group serves as an excellent leaving group for nucleophilic substitution reactions. The PEG4 spacer enhances water solubility, flexibility, and reduces steric hindrance, ensuring efficient conjugation. This reagent is widely applied in drug discovery, bioconjugation, and materials science for designing multifunctional molecules, linkers, and advanced therapeutic or diagnostic platforms.