11-Keto fusidic acid

• CAT Number: R012870
• CAS Number: 16711-91-4
• Molecular Formula: C31H46O6
• Molecular Weight: 514.69
• Purity: ≥95%
• Synonyms: (2Z)-2-[(3R,4S,5S,8S,9S,10S,13R,14S,16S)-16-acetyloxy-3-hydroxy-4,8,10,14-tetramethyl-11-oxo-1,2,3,4,5,6,7,9,12,13,15,16-dodecahydrocyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid

11-Keto fusidic acid（Cat No.:R012870）is a derivative of fusidic acid, a steroid-like antibiotic primarily effective against Gram-positive bacteria, especially Staphylococcus aureus. The 11-keto modification alters its metabolic and antimicrobial properties, making it a valuable compound in studying structure-activity relationships of fusidane antibiotics. Like its parent compound, it inhibits bacterial protein synthesis by targeting elongation factor G (EF-G), thereby halting translation. Researchers use 11-keto fusidic acid in pharmacological and microbiological investigations to explore resistance mechanisms, optimize antibiotic design, and evaluate therapeutic potential against drug-resistant bacterial infections.