11-Azidoundecanoic acid

• CAT Number: I042600
• CAS Number: 118162-45-1
• Molecular Formula: C11H21N3O2
• Molecular Weight: 227.30
• Purity: ≥95%
• Synonyms: 11-azidoundecanoic acid
• InChI: InChI=1S/C11H21N3O2/c12-14-13-10-8-6-4-2-1-3-5-7-9-11(15)16/h1-10H2,(H,15,16)
• InChIKey: LXAVFOAOGZWQKT-UHFFFAOYSA-N
• SMILES: C(CCCCCN=[N+]=[N-])CCCCC(=O)O

11-Azidoundecanoic acid (Cat No.: I042600) is a long-chain azido fatty acid featuring an 11-carbon backbone with a terminal azide group. It is widely used as a bioorthogonal reagent in click chemistry, enabling efficient and selective conjugation to alkynes. This versatile molecule is employed in bioconjugation, surface modification, and drug delivery systems, particularly for creating azide-functionalized surfaces or tagging biomolecules. Its compatibility with copper-catalyzed azide-alkyne cycloaddition (CuAAC) makes it an essential tool in chemical biology and materials science applications.

Reference

[1]. Fernández-Suárez M, et al. Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes. Nat Biotechnol. 2007 Dec;25(12):1483-7.
[Content Brief]

[2]. Heal WP, et al. N-Myristoyl transferase-mediated protein labelling in vivo. Org Biomol Chem. 2008 Jul 7;6(13):2308-15.
[Content Brief]