10-thiastearic acid

• CAT Number: M006237
• CAS Number: 105099-89-6
• Molecular Formula: C17H34O2S
• Molecular Weight: 302.517
• Purity: ≥95%
• Synonyms: 10-thiastearic acid
• Storage: -20°C
• IUPAC Name: 9-octylsulfanylnonanoic acid
• InChI: InChI=1S/C17H34O2S/c1-2-3-4-5-9-12-15-20-16-13-10-7-6-8-11-14-17(18)19/h2-16H2,1H3,(H,18,19)
• InChIKey: OMIBNTWPNMKIGZ-UHFFFAOYSA-N
• SMILES: CCCCCCCCSCCCCCCCCC(=O)O

Heteroatom-<wbr></wbr>substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools. 10-Thiastearic acid inhibits desaturation of radiolabeled stearate to oleate in rat hepatocytes and hepatoma cells by more than 80% at a concentration of 25 µM. This activity is associated with a hypolipidemic effect, making this 10-thiastearic acid a useful tool for evaluating new anti-<wbr></wbr>obesity therapeutics.