1-Palmitoyl-2-oleoyl-sn-glycero-3-PE

• CAT Number: I040352
• CAS Number: 26662-94-2
• Molecular Formula: C39H76NO8P
• Molecular Weight: 718.00
• Purity: ≥95%
• Synonyms: [(2R)-1-[2-aminoethoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (Z)-octadec-9-enoate
• InChI: InChI=1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17-/t37-/m1/s1
• InChIKey: FHQVHHIBKUMWTI-OTMQOFQLSA-N
• SMILES: CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCN)OC(=O)CCCCCCCC=CCCCCCCCC

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (POPE)(CAT: I040352) is a zwitterionic phospholipid composed of a palmitoyl (C16:0) and an oleoyl (C18:1) fatty acyl chain esterified to a glycerol backbone with a phosphoethanolamine headgroup. As a major component of bacterial and mitochondrial membranes, POPE plays a crucial role in membrane fluidity, curvature, and protein-lipid interactions. It is widely used in liposome formation, membrane fusion studies, and reconstitution of membrane proteins. Due to its ability to adopt non-bilayer phases, POPE is valuable for investigating lipid polymorphism and vesicle dynamics. This lipid supports advanced research in structural biology, drug delivery systems, and synthetic membrane modeling.