1-Oxaspiro[4.5]decan-8-one

• CAT Number: L030912
• CAS Number: 87151-60-8
• Molecular Formula: C9H14O2
• Molecular Weight: 154.21
• Purity: ≥95%
• IUPAC Name: 1-oxaspiro[4.5]decan-8-one
• InChI: InChI=1S/C9H14O2/c10-8-2-5-9(6-3-8)4-1-7-11-9/h1-7H2
• InChIKey: RPABADYMEMUBEC-UHFFFAOYSA-N
• SMILES: C1CC2(CCC(=O)CC2)OC1

1-Oxaspiro[4.5]decan-8-one(CAT: L030912) is a spirocyclic compound featuring a fused tetrahydrofuran and cyclohexanone ring system joined at a single quaternary carbon (spiro center). This unique structural motif imparts rigidity and three-dimensional character, making it a valuable scaffold in medicinal chemistry, materials science, and organic synthesis. The ketone functionality at the 8-position allows for further derivatization, including reduction, condensation, and nucleophilic additions. Its spirocyclic architecture is often explored in the design of enzyme inhibitors, bioactive molecules, and conformationally constrained ligands. 1-Oxaspiro[4.5]decan-8-one is ideal for building structurally novel molecules with defined stereochemistry and synthetic versatility.