1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

For research use only. Not for therapeutic Use.

  • CAT Number: R011934
  • CAS Number: 6974-32-9
  • Molecular Formula: C28H24O9
  • Molecular Weight: 504.49
  • Purity: ≥95%
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1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose(CAT: R011934) is a protected ribose sugar derivative commonly used as a key intermediate in nucleoside and nucleotide synthesis. The acetyl group at the anomeric position facilitates glycosylation, while the benzoyl protections at the 2-, 3-, and 5-hydroxyl groups enhance solubility in organic solvents and provide selective deprotection routes. This compound enables the stereoselective construction of β-glycosidic bonds essential for synthesizing purine and pyrimidine nucleoside analogs. It is widely utilized in the development of antiviral and anticancer agents, as well as in carbohydrate chemistry and oligonucleotide modification.


CAS Number 6974-32-9
Synonyms

β-D-Ribofuranose 1-Αcetate 2,3,5-Tribenzoate; 1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribose; 2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl Acetate; ABR; NSC 23349;

Molecular Formula C28H24O9
Purity ≥95%
Storage -20°C
IUPAC Name [(2R,3R,4R,5S)-5-acetyloxy-3,4-dibenzoyloxyoxolan-2-yl]methyl benzoate
InChI InChI=1S/C28H24O9/c1-18(29)34-28-24(37-27(32)21-15-9-4-10-16-21)23(36-26(31)20-13-7-3-8-14-20)22(35-28)17-33-25(30)19-11-5-2-6-12-19/h2-16,22-24,28H,17H2,1H3/t22-,23-,24-,28-/m1/s1
InChIKey GCZABPLTDYVJMP-CBUXHAPBSA-N
SMILES CC(=O)OC1C(C(C(O1)COC(=O)C2=CC=CC=C2)OC(=O)C3=CC=CC=C3)OC(=O)C4=CC=CC=C4
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