1-Methylazetidine-3-carboxylic acid

• CAT Number: L043872
• CAS Number: 875629-26-8
• Molecular Formula: C5H9NO2
• Molecular Weight: 115.13
• Purity: ≥95%
• IUPAC Name: 1-methylazetidine-3-carboxylic acid
• InChI: InChI=1S/C5H9NO2/c1-6-2-4(3-6)5(7)8/h4H,2-3H2,1H3,(H,7,8)
• InChIKey: OQTWISXQJKXTEM-UHFFFAOYSA-N
• SMILES: CN1CC(C1)C(=O)O

1-Methylazetidine-3-carboxylic acid（Cat No.:L043872）is a four-membered nitrogen-containing heterocycle featuring a methyl group on the nitrogen atom and a carboxylic acid group at the 3-position. This compact, strained ring structure imparts unique electronic and conformational properties, making it a valuable non-proteinogenic amino acid in peptidomimetic and pharmaceutical chemistry. Its incorporation into peptides can restrict flexibility, enhancing metabolic stability and receptor selectivity. The molecule’s combination of basicity (from the azetidine ring) and acidity (from the carboxyl group) makes it versatile in designing biologically active compounds and enzyme inhibitors with defined stereochemical and functional attributes.