1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

• CAT Number: L019378
• CAS Number: 837392-62-8
• Molecular Formula: C15H20BNO2
• Molecular Weight: 257.14
• Purity: ≥95%
• IUPAC Name: 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole
• InChI: InChI=1S/C15H20BNO2/c1-14(2)15(3,4)19-16(18-14)12-6-7-13-11(10-12)8-9-17(13)5/h6-10H,1-5H3
• InChIKey: JQLYKUPEQYNDFF-UHFFFAOYSA-N
• SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)N(C=C3)C

1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole(CAT: L019378) is a boronic ester-functionalized indole derivative, featuring a pinacol boronate group at the 5-position and a methyl substituent at the nitrogen (1-position). This compound is a highly useful building block in Suzuki–Miyaura cross-coupling reactions, enabling the formation of C–C bonds in the synthesis of complex molecules. The indole core is a privileged scaffold in medicinal chemistry, often used in the development of anticancer, anti-inflammatory, and CNS-active agents. The boronic ester moiety enhances stability and reactivity, making this compound ideal for the modular construction of bioactive heterocycles, fluorophores, and functional materials in organic and pharmaceutical synthesis.