1-Linoleoyl-rac-glycerol

  • CAT Number: R001609
  • CAS Number: 2277-28-3
  • Molecular Formula: C21H38O4
  • Molecular Weight: 354.5
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Platelet-<wbr></wbr>activating factor (PAF) is a biologically active phospholipid synthesized by a variety of stimulated cells that acts as a mediator of platelet aggregation, inflammation, and allergy. PAF is converted to the biologically inactive lyso-<wbr></wbr>PAF by the enzyme PAF acetylhydrolase (PAF-<wbr></wbr>AH). Recently, plasma PAF-<wbr></wbr>AH has been linked to atherosclerosis and may be a positive risk factor for coronary heart disease in humans. 1-<wbr></wbr>Linoleoyl glycerol (1-<wbr></wbr>LG) is a fatty acid glycerol that has been isolated from <em>S. chinensis</em> roots. It inhibits PAF-<wbr></wbr>AH with an IC<sub>50</sub> of 45 µM. 1-<wbr></wbr>LG has potential application in cholesterol lowering and antiatherogenic activity.

Catalog Number R001609
CAS Number 2277-28-3
Molecular Formula

C21H38O4

Purity 95%
Storage -80°C
InChIKey WECGLUPZRHILCT-HZJYTTRNSA-N

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