1-Isothiocyanato-PEG4-alcohol

For research use only. Not for therapeutic Use.

  • CAT Number: I016564
  • CAS Number: 1835759-69-7
  • Molecular Formula: C9H17NO4S
  • Molecular Weight: 235.30
  • Purity: ≥95%
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1-Isothiocyanato-PEG4-alcohol(CAT: I016564) is a heterobifunctional polyethylene glycol linker featuring a reactive isothiocyanate group and a terminal hydroxyl group. The isothiocyanate moiety enables stable conjugation to primary amines on proteins, peptides, or other biomolecules through thiourea bond formation, while the hydroxyl group offers flexibility for further chemical modification or derivatization. The PEG4 spacer provides enhanced solubility, reduced steric hindrance, and improved biocompatibility, making it a valuable tool for bioconjugation, drug delivery, and surface modification applications. This reagent is widely used in biomedical research, diagnostics, and material science where controlled and versatile molecular linking strategies are required


CAS Number 1835759-69-7
Synonyms

2-[2-[2-(2-isothiocyanatoethoxy)ethoxy]ethoxy]ethanol

Molecular Formula C9H17NO4S
Purity ≥95%
IUPAC Name 2-[2-[2-(2-isothiocyanatoethoxy)ethoxy]ethoxy]ethanol
InChI InChI=1S/C9H17NO4S/c11-2-4-13-6-8-14-7-5-12-3-1-10-9-15/h11H,1-8H2
InChIKey ZFBITNPIULLZRY-UHFFFAOYSA-N
SMILES C(COCCOCCOCCO)N=C=S
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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