[1-(Hydroxymethyl)-3,3-dimethoxycyclobutyl]methanol

• CAT Number: L028646
• CAS Number: 130369-33-4
• Molecular Formula: C8H16O4
• Molecular Weight: 176.21
• Purity: ≥95%
• IUPAC Name: [1-(hydroxymethyl)-3,3-dimethoxycyclobutyl]methanol
• InChI: InChI=1S/C8H16O4/c1-11-8(12-2)3-7(4-8,5-9)6-10/h9-10H,3-6H2,1-2H3
• InChIKey: BCXOBYJPCUTNTN-UHFFFAOYSA-N
• SMILES: COC1(CC(C1)(CO)CO)OC

[1-(Hydroxymethyl)-3,3-dimethoxycyclobutyl]methanol（Cat No.:L028646）is a cyclobutane-based diol compound featuring two hydroxymethyl groups and two methoxy substituents at the 3-position. Its rigid, strained four-membered ring imparts unique steric and electronic properties, making it a valuable intermediate in the synthesis of complex molecules, including pharmaceuticals and fine chemicals. The dual hydroxyl functionality allows for further chemical modification, such as esterification or etherification, while the dimethoxy groups provide electron-donating effects that influence reactivity. This compound is especially useful in developing molecular frameworks with conformational constraints for structure–activity relationship studies.