1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester

• CAT Number: R007375
• CAS Number: 112811-71-9
• Molecular Formula: C16H15F2NO4
• Molecular Weight: 323.30
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: ethyl 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxoquinoline-3-carboxylate
• InChI: InChI=1S/C16H15F2NO4/c1-3-23-16(21)10-7-19(8-4-5-8)13-9(14(10)20)6-11(17)12(18)15(13)22-2/h6-8H,3-5H2,1-2H3
• InChIKey: XPAOPAPDCRLMTR-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=CN(C2=C(C(=C(C=C2C1=O)F)F)OC)C3CC3

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester(CAT: R007375) is a fluoroquinolone-based compound commonly used as a synthetic intermediate in antibacterial drug development. Featuring a quinolone core with difluoro substitution, a methoxy group at the 8-position, and a cyclopropyl moiety at N-1, it mirrors key structural motifs found in bioactive fluoroquinolones. The ethyl ester enhances solubility and facilitates further derivatization in medicinal chemistry workflows. This compound is valuable in structure-activity relationship (SAR) studies targeting bacterial DNA gyrase and topoisomerase IV. Its design supports exploration of antimicrobial properties and pharmacokinetics, making it a useful tool in anti-infective research and early-stage drug discovery.