1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid

• CAT Number: R024906
• CAS Number: 93107-30-3
• Molecular Formula: C13H9F2NO3
• Molecular Weight: 265.22
• Purity: ≥95%
• Synonyms: 1-Cyclopropyl-1,4-dihydro-6,7-difluoro-4-oxoquinoline-3-carboxylic Acid; 1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinolin-3-carboxylic Acid;?1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid;?1-Cyclopropyl-6,7-difluoro-4-oxo
• Storage: Room temperature
• IUPAC Name: 1-cyclopropyl-6,7-difluoro-4-oxoquinoline-3-carboxylic acid
• InChI: InChI=1S/C13H9F2NO3/c14-9-3-7-11(4-10(9)15)16(6-1-2-6)5-8(12(7)17)13(18)19/h3-6H,1-2H2,(H,18,19)
• InChIKey: KNEXGVPHPGXAGF-UHFFFAOYSA-N
• SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)F)F)C(=O)O

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid(CAT: R024906) is a key fluorinated quinolone derivative, structurally related to fluoroquinolone antibiotics. Featuring a cyclopropyl group at the N-1 position and fluorine atoms at the 6 and 7 positions, this compound exhibits enhanced antibacterial properties through inhibition of bacterial DNA gyrase and topoisomerase IV. The 4-oxo and 3-carboxylic acid groups are critical for metal ion chelation and target binding. It serves as a crucial intermediate or core scaffold in the synthesis of potent, broad-spectrum antibacterial agents. Its well-defined structure supports SAR studies and the development of next-generation anti-infectives for pharmaceutical research and drug discovery applications.