1-Cyclohexyl-3-dodecyl urea

• CAT Number: I016834
• CAS Number: 402939-18-8
• Molecular Formula: C19H38N2O
• Molecular Weight: 310.52
• Purity: ≥95%
• Synonyms: 1-cyclohexyl-3-dodecylurea
• InChI: InChI=1S/C19H38N2O/c1-2-3-4-5-6-7-8-9-10-14-17-20-19(22)21-18-15-12-11-13-16-18/h18H,2-17H2,1H3,(H2,20,21,22)
• InChIKey: POEWFBSYPFIYSK-UHFFFAOYSA-N
• SMILES: CCCCCCCCCCCCNC(=O)NC1CCCCC1

1-Cyclohexyl-3-dodecyl urea(CAT: I016834) is a synthetic long-chain urea derivative frequently used as a biochemical probe in studies of lipid metabolism and enzyme regulation. Structurally, it combines a hydrophobic dodecyl chain with a cyclohexyl-substituted urea core, allowing interactions with lipid bilayers and hydrophobic enzyme pockets. This compound has been reported as an inhibitor of soluble epoxide hydrolase (sEH), an enzyme involved in the metabolism of epoxyeicosatrienoic acids (EETs) that regulate vascular tone, inflammation, and renal function. Through sEH inhibition, 1-Cyclohexyl-3-dodecyl urea supports research in cardiovascular disease, hypertension, renal physiology, and inflammatory pathways, serving as a useful tool for pharmacological studies.