1-Bromo-4-(1,1-difluoroethyl)benzene

• CAT Number: L012296
• CAS Number: 1000994-95-5
• Molecular Formula: C8H7BrF2
• Molecular Weight: 221.04
• Purity: ≥95%
• IUPAC Name: 1-bromo-4-(1,1-difluoroethyl)benzene
• InChI: InChI=1S/C8H7BrF2/c1-8(10,11)6-2-4-7(9)5-3-6/h2-5H,1H3
• InChIKey: QXIBKCFAFRHORF-UHFFFAOYSA-N
• SMILES: CC(C1=CC=C(C=C1)Br)(F)F

1-Bromo-4-(1,1-difluoroethyl)benzene(CAT: L012296) is a halogenated aromatic compound featuring both a bromine and a difluoroethyl group on a benzene ring. This compound is a valuable building block in medicinal and agrochemical synthesis, offering a dual handle for further functionalization. The bromine atom enables cross-coupling reactions such as Suzuki or Heck, while the difluoroethyl group introduces desirable fluorine-related properties like enhanced metabolic stability, lipophilicity, and bioavailability. It is particularly useful in the development of fluorinated pharmaceuticals, advanced materials, and radiolabeled compounds for imaging. Its reactivity and fluorinated moiety make it ideal for modern fluorine chemistry and structure–activity relationship studies.