1-Bromo-2-chlorobenzene

• CAT Number: R070162
• CAS Number: 694-80-4
• Molecular Formula: C6H4BrCl
• Molecular Weight: 191.45
• Purity: ≥95%
• Synonyms: 2-Bromochlorobenzene
• Storage: RT
• IUPAC Name: 1-bromo-2-chlorobenzene
• InChI: InChI=1S/C6H4BrCl/c7-5-3-1-2-4-6(5)8/h1-4H
• InChIKey: QBELEDRHMPMKHP-UHFFFAOYSA-N
• SMILES: C1=CC=C(C(=C1)Cl)Br

1-Bromo-2-chlorobenzene(CAT: R070162) is a halogenated aromatic compound featuring a benzene ring substituted with bromine and chlorine atoms in adjacent (ortho) positions. This dual-halogen configuration makes it a versatile intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki, Stille, or Buchwald–Hartwig couplings. It is widely used in the development of pharmaceuticals, agrochemicals, and advanced materials, where selective functionalization of the aromatic ring is required. The presence of both electron-withdrawing halogens enhances its reactivity and regioselectivity in substitution and metalation reactions.