1-Boc-3-azetidinone

• CAT Number: R051120
• CAS Number: 398489-26-4
• Molecular Formula: C8H13NO3
• Molecular Weight: 171.20
• Purity: ≥95%
• Synonyms: 3-Oxo-1-azetidinecarboxylic Acid 1,1-Dimethylethyl Ester; 1-Boc-3-oxo-azetidine; 1-tert-Butoxycarbonyl-3-azetidinone; 3-Oxoazetidine-1-carboxylic Acid tert-Butyl Ester; 3-Oxoazetidine-1-carboxylic Acid tert-Butyl Ester; tert-Butyl 3-Oxoazetidine-?1-c
• Storage: -20°C
• IUPAC Name: tert-butyl 3-oxoazetidine-1-carboxylate
• InChI: InChI=1S/C8H13NO3/c1-8(2,3)12-7(11)9-4-6(10)5-9/h4-5H2,1-3H3
• InChIKey: VMKIXWAFFVLJCK-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CC(=O)C1

1-Boc-3-azetidinone (Cat No.: R051120) is a protected four-membered β-lactam derivative with the molecular formula C₈H₁₃NO₃. It features a Boc (tert-butoxycarbonyl) protecting group on the nitrogen atom and a ketone at the 3-position of the azetidine ring. This compound is widely used as a versatile intermediate in organic synthesis, particularly in the development of pharmaceuticals and biologically active molecules. The strained ring system combined with the Boc group makes it suitable for nucleophilic ring-opening reactions, peptide synthesis, and the construction of complex nitrogen-containing scaffolds.