1-Aminobicyclo[2.2.2]octane

• CAT Number: M047412
• CAS Number: 1193-42-6
• Molecular Formula: C8H15N
• Molecular Weight: 125.215
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: bicyclo[2.2.2]octan-4-amine
• InChI: InChI=1S/C8H15N/c9-8-4-1-7(2-5-8)3-6-8/h7H,1-6,9H2
• InChIKey: VCLQDVVELGHZMQ-UHFFFAOYSA-N
• SMILES: C1CC2(CCC1CC2)N

1-Aminobicyclo[2.2.2]octane, also known as quinuclidine, is a bicyclic amine with a nitrogen atom at the 1-position of the bicyclic structure. The rigid, strained ring system imparts unique chemical properties, including high basicity and nucleophilicity at the nitrogen. Quinuclidine is widely used as a strong organic base, a catalyst in organic reactions, and in the synthesis of pharmaceuticals. It has applications in medicinal chemistry, particularly for the development of neuromodulatory agents and other biologically active compounds.