1-(5-Chloronaphthalenesulfonyl)-1H-hexahydro-1,4-diazepine, Hydrochloride

  • CAT Number: R020650
  • CAS Number: 105637-50-1
  • Molecular Formula: C15H18Cl2N2O2S
  • Molecular Weight: 361.281
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ML 9 a is myosin light chain kinase (MLCK) inhibitor. ML-9 enhances the anticancer activity of docetaxel, suggesting its potential application as an adjuvant to existing anticancer chemotherapy. The complex effect of ML-9 on autophagy and indentified ML-9 as an attractive tool for targeting autophagy in cancer therapy through dual inhibition of both the Akt pathway and the autophagy.

Catalog Number R020650
CAS Number 105637-50-1
Molecular Formula


Purity 95%
Target Myosin
Solubility Soluble in DMSO > 10 mM
Storage Desiccate at RT
IUPAC Name 1-(5-chloronaphthalen-1-yl)sulfonyl-1,4-diazepane;hydrochloride
InChI InChI=1S/C15H17ClN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H

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